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And when something doesnt feel right, patients may not have a provider who knows their health history well enough to guide them

[1] Contact your GP or NHS 111 if: Gastrointestinal side effects persist beyond the first few weeks or worsen over time Diarrhoea persists for more than a few days or is accompanied by fever Constipation becomes severe or does not respond to dietary measures and over-the-counter remedies You experience unexplained weight loss beyond expected therapeutic effects Symptoms significantly impact your quality of life or ability to maintain nutrition You have concerns about any new or unusual symptoms Patients with known diverticular disease should maintain regular contact with their healthcare team and report any changes in bowel habits or abdominal symptoms promptly

This may lead to reduced secretion of luteinising hormone and follicle-stimulating hormone, potentially causing anovulation and menstrual irregularities including missed periods

Notably, BMI and A1c were similar between cohorts at baseline and follow-up, suggesting the lower rates of nonexudative or any AMD with GLP-1 RAs are not readily explained by weight loss or glycemic control, though residual time-varying mediation cannot be excluded, this studys authors wrote in their paper

Symptoms were rated as mild to moderate in nearly all reported cases, and nobody in the available research stopped using the medication because of skin-related issues alone