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You may refrigerate an opened vial at 2 to 8C if you prefer, but it does not extend the 28-day window

Exactly where on your body you feel it and whether it moves

Reduced serum electrolyte content can come from sustained exercise in hot weather, persistent expulsions like vomiting or diarrhea, or simply eating too little, for too long

5-12 The most common patient-reported adverse effects (AEs) associated with GLP-1 RAs and dual GIP/GLP-1 RAs are gastrointestinal (GI) in nature and may include abdominal pain, constipation, diarrhea, nausea, and vomiting

It is thought to bind to these receptors and potentially trigger several responses, such as enhancing gut motility and improving nutrient absorption