However, in NDDs, chronic or overwhelming ER stress shifts the UPR toward maladaptive responses, contributing to neuronal dysfunction and death, e.g., Prolonged PERK activation has been implicated in AD, PD, and ALS, where it contributes to chronic ER stress and neuronal death
Alterations of the human gut microbiome in liver cirrhosis
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Mezcla de fibras para el control de la diarrea en un paciente durante el tratamiento oncolgico: un caso clnico