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The SNPs can affect vitamins B6, B12, and folate, whereas vitamins B1, B2, B3, B5, and B7 are not affected by the MTHFR variants

They are commonly used for conditions like cervical radiculopathy, spinal stenosis, and disc disorders

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Retatrutides Phase 2 monotherapy weight loss (~24.2% at 48 weeks) is numerically larger than cagrilintides (~10.8% at 26 weeks), but those come from different trials, durations, and doses, and cagrilintides strongest data are as the CagriSema combination