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The expiry of semaglutide patents in India and Canada (January 2026) and Brazil (March 2026) opens the doors for affordable alternatives to penetrate emerging markets, where obesity and diabetes are growing public health challenges
Prior to that, Rybelsus was the only FDA approved GLP-1 drug available in pill form, but it was approved for diabetes control and only used secondarily (or, "off label") for weight loss
Researchers believe semaglutide may influence aging through several pathways
Prophylactic bosentan does not improve exercise capacity or lower pulmonary artery systolic pressure at high altitude
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