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These older medications produce less dramatic weight loss compared to semaglutide and tirzepatide, which supports the theory that the rate and magnitude of weight loss, rather than the GLP-1 receptor activation itself, drives most of the hair shedding
To establish a correlation between the peak area of HPLC and Dox concentration, we plotted a calibration curve, as shown in Supplementary Fig
95% CI, -6.7 to -4.3
These two receptor systems overlap in some functions and diverge in others
This weight reduction persists long-term, with patients maintaining significant weight loss for up to four years
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