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Hensley, M
van Haeften, T
As a one-off, this may not be an issue, but if youre drinking regularly (think several heavy nights over Christmas) it could increase your risk of a deficiency of B vitamins and folic acid, both of which keep you firing on all cylinders
For example, if a patient gets 1000 mcg in 1 mL of 1000 mcg/mL solution, changing to 500 mcg/mL means you need 2 mL to get the same dose
These factors suggest starting slightly higher than the minimum effective clinical dose to account for real-world variability
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