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The concentration of the buffer in the pharmaceutical formulation containing cagrilintide must also be low enough to prevent it from being ejected from the device and injected into the individual (and therefore mixed with the pharmaceutical formulation containing semaglutide) , PH drops to a level where semaglutide will precipitate or form particles

When drugs are in short supply, the FDA can allow temporary compounding of some medicines so that patients can access their treatments

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