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A common functional polymorphism at codons 108 and 158 in the genes coding for SCOMT and MBCOMT (COMT Val 108/158 Met), respectively, has been examined in relationship to a number of neurological disorders involving the noradrenergic or dopaminergic systems, such as schizophrenia (Park et al., 2002) or Parkinson's disease (Kunugi et al., 1997)
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Most cases relate to rapid weight reduction triggering telogen effluviuma temporary shedding phaserather than direct drug toxicity
About 8 percent of adults considered GLP-1s extremely risky in February 2026 compared to 15 percent in May 2024
