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For others, especially those needing nerve or anemia support, improvements might take weeks or months with consistent injections
[11] Long-term metformin therapy reduces calcium-dependent intrinsic-factor binding, lowering B12 absorption and potentially necessitating higher or more frequent parenteral doses
Its effectiveness isnt just about the vitaminits also about where its injected
Some people, particularly those who were severely deficient, report a sudden improvement in energy, focus, or mood within 24 to 72 hours
According to the NIH Office of Dietary Supplements, vitamin B12 is available as cyanocobalamin and hydroxocobalamin, which are typically administered parenterally by intramuscular injection to bypass gastrointestinal absorption barriers
