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RT-qPCR analyses validated the upregulation of ATF4 target genes, including SLC1A1, SLC7A8 , phosphoserine aminotransferase 1 ( PSAT1 ), and serine hydroxymethyltransferase 2 ( SHMT2 ) in T315I-Bcr-Abl cells (Fig

Research demonstrates that co-administration produces amplified GH pulses exceeding the sum of individual peptide effects, suggesting receptor-level synergism between GHRH and ghrelin pathway activation

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