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No variants that fulfilled the criteria to be likely pathogenic or pathogenic according to the American College of Medical Genetics and Genomics (ACMG) that could explain a metabolic disorder with an autosomal recessive inheritance were identified [22]

TRIM37 consists of a Really Interesting New Gene (RING) domain, B-box motifs, a coiled-coil region, and a meprin and TRAF homology (MATH) domain at its C-terminus

Enhanced GIP secretion in obesity is associated with biochemical alteration and miRNA contribution to the development of liver steatosis

However, repetitive motion or overload on muscles triggers the risk