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So, while DPP-IVs may offer a better gastrointestinal (GI) adverse event profile than GLP-1RAs, they are generally less effective at reducing HbA 1C and have a lower potential for weight loss

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The metabolic improvements from tirzepatide, reduced blood pressure, improved lipid profiles, better glycemic control, and reduced inflammation, directly address the leading cause of death in men

Moderate age-related decline necessitates more stimulation than younger patients but most retain adequate pituitary reserve for good response