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Name: surmount studies tirzepatide surmount-1 trial obesity without diabetes Gastrointestinal tolerability and weight reduction associated with in adults SURMOUNT-1
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10.1080/10408398.2020.1865871 21 HeC.GaoM.ZhangX.LeiP.YangH.QingY.et al (2022)

Repurposing metformin to treat age-related neurodegenerative disorders and ischemic stroke

We found that (1) GLP-1R KO mice exhibit impaired brain glucose metabolism to high doses of exogenous glucose

This translates into a total growth of 700% , with the market forecast to expand at a compound annual growth rate (CAGR) of 23.1% between 2025 and 2035

Others dismiss it entirely because large-scale human clinical trials are still lacking