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Proc Natl Acad Sci U S A 104:1201712022
Injections may be given daily for several days to a week, then weekly for several weeks
Those who survive can be burdened with motor or cognitive impairments that severely reduce their quality of life
Among the outcome estimates, significant reductions were reported in 13 of 17 for major adverse cardiovascular events (MACE), 5 of 8 for cardiovascular mortality, 3 of 4 for cardiovascular disease (CVD) events, 1 of 3 for cardiovascular death, and 1 of 1 for composite cardiovascular outcomes
(A) Area of melanotic encapsulation (ME) (mm2)
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