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doi: 10.1056/NEJMoa1901118 55 RosenstockJAllisonDBirkenfeldALBlicherTMDeenadayalanSJacobsenJBet al

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Common side effects like nausea typically improve within 4-8 weeks

While tirzepatide 2.5 mg is not intended as a maintenance dose, select patients may achieve clinically meaningful glycemic control at lower doses, emphasizing the importance of patient-specific assessment rather than rigid adherence to population-level dosing assumptions