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First, we emulated the two cardiovascular outcome trials SUSTAIN-6 (semaglutide versus placebo) and SURPASS-CVOT (tirzepatide versus dulaglutide) using the RCT-DUPLICATE approach to benchmark findings and inform the study design and analytic approach for expanded questions

(8) PT-141 peptide is available for research and laboratory purposes only

10.1161/CIRCHEARTFAILURE.108.766402

Many patients using GLP-1 therapy report better endurance, improved sleep, steadier energy, and an overall feeling of being more balanced and capable

The table below shows how often specific reactions were reported in each drugs FDA approval trials