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Hiccups are not listed as an adverse reaction in the Summary of Product Characteristics (SmPC) for either medication, though some patients have reported experiencing persistent or troublesome hiccups during treatment

These symptoms are typically most noticeable during dose escalation and tend to improve as the body adjusts

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Drug Interactions and Compatibility 11.1 Interaction with Oral Antidiabetic Medications Semaglutide may be co-administered with oral antidiabetic agents, yet pharmacodynamic interactions require careful calibration