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Xie T, McCann UD, Kim S, Yuan J, Ricaurte GA (2000)
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If metformin at a maximum tolerated dose does not achieve the HbA1c target after 3 months, add a second oral agent (a sulfonylurea [SU], thiazolidinedione [TZD], dipeptidyl peptidase 4 [DPP-4] inhibitor, or sodium-glucose cotransporter-2 [SGLT2] inhibitor), a glucagon-like peptide-1 (GLP-1) receptor agonist, or a basal insulin ( TABLE 2 )
Mechanism of Action Compared AOD-9604 and Tesamorelin both influence fat metabolism, but through opposite ends of the growth hormone system: AOD-9604 acts directly on fat cells without engaging the GH/IGF-1 axis at all, while Tesamorelin works by turning that axis on
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