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Therapeutic modulation of virus-induced oxidative stress via the Nrf 2-dependent antioxidative pathway

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| The standard metabolic stack remains the most widely adopted design in published research because it balances efficacy with practical adherence

According to the classic two-hits model, the increased insulin resistance, secondary to metabolic syndrome, determines an excessive lipid accumulation in healthy hepatocytes (first hit), mainly through an increased mobilization of free fatty acids from visceral adipose tissue to the liver