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IL-10 is especially recognized as a preeminent anti-inflammatory and multifunctional cytokine within the immune framework (249)

Supporting this, chronic inflammation can worsen symptom severity and affects treatment responsiveness [105, 106], and certain classes of antidepressant medications have anti-inflammatory effects [107,108,109,110] and vice versa [111, 112]

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Cai J, Chen Y, Seth S, Furukawa S, Compans RW, Jones DP