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The expression and activity of glutaminolytic enzymes, GLS and GDH, are also tightly regulated

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The most commonly reported effects include: Mild water retention during the first 2 to 4 weeks Occasional headaches, particularly at treatment initiation Redness or irritation at the injection site Tingling or numbness in the extremities Short term fatigue or flushing after injection Ipamorelins selectivity provides a meaningful safety advantage