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For skin-specific research, topical delivery has four practical advantages that shape research protocol design
Mitopure (Urolithin A), for example, enhances mitochondrial function through a process called mitophagy and is clinically proven to improve muscle strength, even in the absence of exercise
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This means that statements about its safety are inherently uncertain, and the absence of reported serious harm in small studies is not the same as proven safety
Sisley S et al
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