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However, some scholars have proposed that the effect of GLP-1 in the liver is indirectly mediated by multiple mechanisms, such as reducing fat absorption or inhibiting fat cells through acyl-CoA synthetase long chain family member 1 (ACSL1), CCAAT/enhancer binding protein (C/EBP), peroxisome proliferator-activated receptor- (PPAR), and sterol regulatory element binding protein-1c (SREBP-1c) pathways to achieve the purpose of reducing liver lipids [38]

Additionally, vitamin B12 is important for energy production

5 While oral delivery already dominates the pharmaceutical landscape accounting for roughly 84% of top-selling medicines 6 GLP-1s introduce greater complexity

February 14, 2020