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Restoring Impaired Associative Learning In a recent study in Nature Metabolism , Hanssen and colleagues showed that a GLP-1 drug (liraglutide), in a small trial (N=24 participants) of people with insulin resistance, with a single-blind, randomized, placebo-controlled crossover design, with functional brain MRIs, that 1 dose normalized impaired learning of sensory associations, supporting that metabolic signals profoundly influence neuronal processing. Reduced Alcohol Drinking and Potential Anti-addiction Drug Effects In the experimental model, Chuong and colleagues published in JCI the impact of GLP-1 drugs to inhibit alcohol intake

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Figure 3 shows an overview of the mentioned effects of the two GLP-1R agonists and their influence on numerous signaling pathways