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CharpentierJWagetAKloppPMagnanCCruciani-GuglielmacciCLeeSJet al
subjects with higher body weight tend to have lower semaglutide exposure [24, 25]
For example, glucose is absorbed by the intestine and enters the portal vein, where glucose sensing increases hepatic vagal signaling to the NTS 52 and subsequently to the hypothalamus 53 to decrease food intake 54,55 and regulate glycemia 56,57
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