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Current evidence does not establish that GLP-1 medications directly cause bone loss, though the substantial weight reduction they produce may influence bone density through indirect mechanisms
Without insurance, the list prices for each are as follows: Mounjaro: $1,069.08/month Wegovy: $1,349.02/month That may not be an enormous disparity, and each company has different savings programs for certain groups, which may further reduce costs
NHS prescription records provide verifiable evidence of authorised medication use if required for any formal inquiry, though such situations are exceptionally rare given that Wegovy is not included in drug screening panels
Therefore, we can conclude that the inhibition of mitochondrial activity by metformin is probably the driver of the phenotype observed here
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