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DPP-4 inhibitors can on the other hand also be combined with an oral therapy with a SGLT-2 inhibitor (in dual combination when metformin is contraindicated or not tolerated or in triple therapy with metformin)

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Staying well-hydrated often prevents or minimizes headaches

This change follows the FDAs 2025 declaration that drug shortages for these medications have been resolved

For laboratory applications, it may be reconstituted with bacteriostatic water or another suitable solvent, following standard peptide-handling protocols