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A 2025 study in the American Journal of Ophthalmology did not find a significant increase in NAION or ischemic optic neuropathy risk in patients taking semaglutide or GLP-1 medications compared with diabetes or high-BMI control groups
Athletes can also experience a short-term increase in inflammatory markers after strenuous exercise
Although the actions of GLP-1 on the beta-cell are preserved yet modestly diminished in T2DM, the diabetic alpha-cell retains near normal responsivity to low dose GLP-1 infusion, with inhibition of glucagon secretion seen to a similar extent in diabetic vs
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