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This direct delivery raises plasma concentrations within minutes, which is why IV remains the preferred route for therapeutic outcomes
DSIP differs from more pathway-specific compounds such as Epitalon and Orexin in that it does not act through a single defined receptor or molecular axis
These obstacles can be overcome by Dihexa, a synthetic, small molecule HGF mimetic that is orally bioavailable, metabolically stable, blood-brain barrier permeable, and inexpensive to synthesize (McCoy et al., 2013)
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albicans , such as pyocyanin (PYO) and 5-methyl-phenazine-1-carboxylic acid (5MPCA) [82, 83]
