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Kidney infections, in particular, are a serious concern because they can lead to severe health issues if not treated promptly

These metabolic benefits often appear before significant weight loss occurs, suggesting mechanisms beyond simple calorie reduction

Baumgartner S

Without a spatially restricted and experimentally identifiable origin of ferroptotic stress, ordered patterns of cell death could simply reflect pre-existing gradients in ferroptosis susceptibility within heterogeneous microenvironments rather than true directional propagation

Additionally, the use of an age cutoff of 65 years may not be representative of an elderly or older population, which would include those aged 75 years and older