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STEP 4 and 10 echoed this, with liraglutide and semaglutide users regaining substantially.[1][2][4] SURMOUNT Trials (Tirzepatide) SURMOUNT-4: After 36 weeks of loss, placebo switch led to near-complete regain over 52 weeks, versus sustained loss on continued drug
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14 GLP1RAs work by potentiating glucosedependent insulin secretion from the cells of the pancreas accompanied by a low risk of hypoglycemia
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