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For example, chondrocytes isolated from OA cartilage displayed significant senescence levels, and ABT263 treatment reduced the expression of inflammatory cytokines and promoted cartilage matrix aggregation in OA chondrocytes ( Next, we tested the potential of FOXO4-DRI in removing senescent chondrocytes, which has not been reported before

Quan L, Xu X, Cui Y, Han H, Hendren RL, Zhao L, et al

This is where supplementation, paired with a healthy lifestyle, becomes useful

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