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Lancet Diabetes Endocrinol 7(11): 834-844
Mechanistically, it acts as a ghrelin mimetic, binding the growth hormone secretagogue receptor (GHS-R1a) the receptor for the endogenous peptide ghrelin, expressed in the pituitary and hypothalamus
The FDA's 503A framework also requires bulk substances used by compounders to meet applicable standards and be accompanied by a valid certificate of analysis, with the agency advising compounders to scrutinise their bulk-drug suppliers
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