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Animal studies have demonstrated that the supplementation of CoQ10 in vitro during the culture of embryos significantly enhances the cleavage rate, blastocyst formation rate, hatching rate, and blastocyst expansion rate of early embryos (Ben-Meir et al., 2015

This review aims to highlight the central role of OS in the pathophysiology of ALS, specifically focusing on the KEAP1-NRF2 system and its alteration in ALS, while discussing the potential applications of NRF2 activators in ALS therapy