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According to the SURMOUNT-5 trial published in May 2025, participants on the maximum tolerated dose of Semaglutide (1.7 mg or 2.4 mg) achieved an average weight loss of 13.7% over 72 weeks
Semaglutide has proven to be a life-changing medication for many people
Advertisement Article continues below this ad For the substantial share of patients who dont meet surgical criteria, or who cant navigate that process, GLP-1 medications were filling a gap the system had otherwise left open
was supported by the Ministerium fr Kultur und Wissenschaft des Landes Nordrhein-Westfalen, Senatsverwaltung fr Wissenschaft, Gesundheit und Pflege Berlin, and by the Bundesministerium fr Bildung und Forschung (BMBF) (for F.-L.H, J.D., E.T., K.L., S.H.)
These findings suggest potential use as an adjunctive therapy in opioid use disorder treatment
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