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Tresiba and all other insulin medications simply provide this hormone exogenously

Continuous use up to 3 to 6 months sometimes occurs under medical monitoring

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SGLT2 inhibitors (Jardiance, Farxiga) help the kidneys by reducing glucose and sodium reabsorption in the kidneys, lowering blood pressure, and reducing protein leakage in urine

For a biologic, this means characterizing the protein sequence, glycosylation pattern, expression system, downstream purification process, and all mechanism-of-action claims associated with each approved and investigational indication