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While the rigorous study confirmed that high-dose CoQ10 was entirely safe and well-tolerated, it did not demonstrate a statistically significant reduction in overall symptom severity compared to the placebo over the 6-week intervention periods

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Its the active ingredient in the antidepressants Wellbutrin and Aplenzin, and in the smoking-cessation aid Zyban

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Hotamisligil, G

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(2025) Di et al

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