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Researchers should anticipate that the glucagon receptor-mediated effects on energy expenditure may manifest earlier in some assays than the full appetite-suppressing effects, given the different tissue distributions of the three receptor types

These types of medications have caused thyroid cancer in animal studies

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This peptide binds to a specific receptor on the surface of beta cells in the pancreas, causing them to release insulin, and for a long time researchers assumed that GLP-1 analogues only affected insulin release, hence why they were prescribed for type 2 diabetes