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When inflammation becomes persistent: Ongoing inflammation can disrupt the skin barrier, slow healing, and increase the likelihood of acne marks and uneven skin tone over time

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The main difference is where the medication is delivered: SubQ injections go just beneath the skin into the fatty tissue layer

In these phase III studies the DPP-4 inhibitors were examined as monotherapy in drug-nave patients and as add-on to on-going therapy with metformin, sulfonylurea therapy, thiazolidinedione therapy and therapy with exogenous insulin in type 2 diabetes (Table 2)