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Whilst the preliminary findings are intriguing and warrant further investigation through properly designed clinical trials, clinicians should counsel patients that any effects on alcohol intake are incidental rather than therapeutic indications

When apoptosis effectors such as BAX are activated, they oligomerize and form macropores in the outer mitochondrial membrane causing mitochondrial outer membrane permeabilization (MOMP) (132)

In July 2023, the EMA initiated an inquiry into safety concerns after receiving approximately 150 spontaneous reports indicating potential links between drugs and suicide ideation or self-harm [72]

Prioritize adequate protein (1.0-1.5 g/kg/day) and fiber (25-38 g daily) intake, stay well-hydrated, practice mindful eating, ensure 7-9 hours of quality sleep, and manage stress