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Tirzepatide is the agonist of GLP-1 receptor and glucose-dependent insulinotropic polypeptide (GIP) receptor, which can reduce body weight and improve cardiac metabolism by subcutaneous injection once a week (Jastreboff et al 2022)

When comparing Akkermansia probiotics for metabolic wellness , it helps to understand how this microbe fits into the larger GLP-1 and microbiome system

short telomeres are associated with increased risk of cardiovascular disease, cancer, and all-cause mortality at the population level Telomerase is the enzyme that rebuilds telomere length

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Gambuzza et al., 2015)