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Acknowledgments We would like to thank Biorender for providing the professionally designed figure elements to the manuscript
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Its effects begin upstream at the pituitary and develop through a multi-step endocrine pathway involving GH, IGF-1, and tissue-specific GH-receptor signaling
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It is well-established that oxidative stress, particularly the accumulation of intracellular reactive oxygen species, is a hallmark of oocyte aging and is exacerbated during extended in vitro culture
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