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Aghili SMM et al (2021) Obesity in COVID-19 era, implications for mechanisms, comorbidities, and prognosis: a review and meta-analysis

GLP-1 agonists and other metabolism-based antiaging interventions like NAD+ or Metformin might more appropriately serve the diverse hallmarks of aging, as they have synergistic effects

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Clinical trials have included both male and female participants, with some notable observations: Metabolic differences Men typically have higher baseline metabolic rates and different fat distribution patterns, which may influence response magnitude but not optimal dosing protocols