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Dose adjustments have to be observed for the various DPP-4 inhibitors with renal elimination in dependence of the compound used and the severity of renal impairment (21, 22, 29, 32)
Opportunities exist in alternative therapeutic areas where there may be more white space for the incretin mimetic class, and these opportunities are garnering the attention of manufacturers (see image 4 below)
Data represent the mean SD of n = 3 experiments performed in biological replicate
Early NAD metabolism and antioxidant defense support, followed by deeper mitochondrial resilience and cellular redox balance with consistent use
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