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These individuals typically have acute injuries with strong inflammatory components
These compounds have been studied for their immunomodulating, anti-inflammatory, neuroprotective, and anti-cancer properties
Two-hit vascular hypothesis of AD Blood vessel damage is thought to be the initial insult through which bloodbrain barrier dysfunction and/or diminished brain perfusion lead directly to amyloid- (A)-independent secondary neuronal injury (first hit) and A accumulation (second hit) in the brain owing to faulty A clearance and increased antibody production
In people with Alzheimer's, pieces of a protein called amyloid cluster together to form plaques between their brain cells, and another protein called tau forms tangles inside their nerve cells
Iron is a key mediator in ROS-induced cellular damage
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