However, antidepressants are still sometimes prescribed to help if patients are experiencing depression ( Treating comorbidities ME/CFS displays an overlap with several autoimmune or immune-mediated diseases that also have chronic fatigue as a main symptom, such as Hashimotos thyroiditis (530), fibromyalgia (FM) (532, 554557), Mast Cell Activation Disorder (532), sleep apnoea (532), IBS (532), secondary depression or anxiety (532), Ehlers-Danlos syndrome (532), and PoTS (532, 558563)
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This is due to the possibility that more glycine and serine may be needed to properly catabolize the extra methionine, unintentionally leading to a shortage in these amino acids
Depression, anxiety, chronic fatigue syndrome, post-COVID syndrome (long COVID), and menopause/perimenopause are also frequently associated with cognitive clouding