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In contrast to prior controlled studies that had produced negative findings, the TACT trial found that chelation therapy modestly improves outcomes for patients with a prior heart attack or history of heart attacks, and markedly improves outcomes if the patients were also diabetic

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*Correspondence: Gang Liu [email protected] These authors have contributed equally to this work This article was submitted to Animal Reproduction - Theriogenology, a section of the journal Frontiers in Veterinary Science ORCID: Shubin Li orcid.org/0000-0002-6865-9667 Jingyu Ren orcid.org/0000-0002-0048-3052 Wenqi Zhang orcid.org/0000-0003-4891-500X Yanfeng Dai orcid.org/0000-0001-7147-1748 Gang Liu orcid.org/0000-0002-5180-3765 Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Juan Pablo Frias, medical director of Velocity Clinical Research, Los Angeles and principal investigator of SUSTAIN FORTE, in a statement

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