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In 2023, a randomized, double-blind, placebo-controlled, multicenter trial investigated the efficacy of tirzepatide over 24 weeks in patients with moderate-to-severe obesity and OSAS

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[PMID 27797785] Lipase increases In trials, lipase increases occurred in 5.3% of Saxenda-treated patients and 2.2% of placebo-treated patients, with levels 3 X ULN occurring in 2.1% and 1%, respectively

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