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En cas de pathologies spcifiques (problmes rnaux), un avis mdical est recommand

The existing evidence, while promising, does not establish efficacy, optimal dosing, treatment duration, or long-term outcomes for this indication

Fatigue or mild headache may occur in some patients during the first day, though these symptoms are less common than gastrointestinal effects

By meta-analysis of the individual cardiovascular endpoints, significant improvements were established for all of the following: myocardial infarction, stroke, cardiovascular mortality, all-cause mortality and hospitalisation for heart failure

Br J Ophthalmol 101:12341237